Muta Mesthri is action based movie in which, Bose (Chiranjeevi) is a very patriotic man who fights for the rights of the local market workers against Aatma, the nearby underworld don. Seeing his dedication for helping the working poor, the chief minister (Gummadi Venkateswara Rao) asks him to enter politics. As a politician, he takes charge of a special branch of commandos and destroys Aatma